The bacteria live on the skin of all and new studies show that some germs produce natural antibiotics that fight other germs that cause diseases. Now, scientists are including these germs beneficial in lotions with the hope of offering protection.
In an initial test, these creams are protected to five patients who had eczema against a bacteria that was accumulating on his skin.
“Is elevating the immunologic defenses of the body,” said dr. Richard Gallo, chief of dermatology at the University of California at San Diego, who is heading the study.
Humans share our bodies with trillions of microbes that live on the skin, the nose and the digestive system. That community —called the microbiota— plays critical roles in our resistance or vulnerability to various diseases. To understand how the microbiota healthy is a huge field of studies, and scientists alter the bacterial population in the digestive system to fight infections causing diarrhoea.
The study released Wednesday sheds light on the microbiota of the skin, indicating that one day it may be possible to restore the proper balance to treat conditions skin.
Healthy skin is home to a different mix of bacteria that damaged skin conditions such as atopic dermatitis, the most common form of eczema. These segments of dry skin red represent a higher risk of infections, especially of the dangerous bacteria Staphylococcus aureus.
The team of Gallo looked closely at how the microbes in the healthy skin might be fighting that staph.
They found that certain variants of some protective bacteria secrete two “peptides antimicrobials”, a type of natural antibiotic. In laboratory tests and in the surface of animal skin, these substances were able to selectively kill the Staph aureus, and even a variant that is resistant to drugs known as MSRA, without killing bacteria surrounding as they would regular antibiotics, reported the team in the journal Science Translational Medicine.
But these germs are beneficial are rare in people who have atopic dermatitis, said Gallo.
“People with this type of eczema, for some reason that we know we still have a lot of bacteria on the skin, but the wrong kind of bacteria. Do not produce antimicrobials that they need,” he said.
The team did tests with five volunteers with atopic dermatitis whose skin was detected Staph aureus, although they did not have the infection. The scientists took bacteria protective of the skin of volunteers, cultured in a larger volume, and mixed with a moisturizing cream regularly. The volunteers rubbed the cream in an altered arm and the regular cream in the other.
A day later, a large part of the staph in the arm treaty had died — in two cases was eradicated, » said Gallo.
Nowadays, there are other clinical trials to examine the effects of a prolonged use of the cream.
“It is really an important study,” said dr. Emma Guttman-Yassky, of the Faculty of Medicine at the Mount Sinai Hospital of New York, who was not involved in the process. “It opens up the opportunity for a new treatment.”