A new method for printing three-dimensional living tissues – https://nmas1.org/

A new method for printing three-dimensional living tissues - https://nmas1.org/ 1

The bioimpresor 3D drops, developed by the Bayley Research Group at Oxford (Sam Olof / Alexander Graham).

A research published in the journal Scientific Reports gives an account of the method developed by scientists from the University of Oxford to print in 3D cultured cells in the laboratory, to form living structures.

Regenerative medicine would be widely beneficial with this advance, to the extent that allows the production of tissue and cartilage complex to repair damaged areas of the body.

It is a series of human and animal cells that can be printed to create tissue structures with high resolution, on the basis of synthetic scaffolds soft, around whom the printed cells and develop. The technique of 3D printing applied to this area has had a complicated process of sophistication, to the extent that it is difficult to control with precision the position of the cells in the structures.

But, led by Professor Hagan Bayley, professor of Chemical Biology in the Department of Chemistry of Oxford, the team devised a way to produce tissues in a cell autonomous support structures to maintain their shape. The cells were contained within droplets protective of nanoliter wrapped in a coating of lipid that could be assembled, layer by layer, in living structures. The production of fabrics printed in this manner improves the survival rate of individual cells and allows the team to improve the current techniques by means of the construction of each fabric, printed drop-by-drop in high resolution. Thus, the artificial tissue are more able to imitate the behaviors and functions of the human body.

Previous experiments unsuccessful in the development of artificial tissues have allowed scientists to Oxford to focus on the design of a platform high print resolution cell, from components that are relatively inexpensive, which may be used to reproduce the production of artificial tissue with the adequate complexity of a range of cells, including stem cells.

The researchers hope that, with further development, the materials can have a large impact on healthcare around the world. Potential applications include the formation of models of human tissues reproducible that could eliminate the need for clinical tests in animals.

The team completed their research last year, and since then measures have been taken to market the technique and make it more widely available. In January 2016, OxSyBio was officially launched outside the Bayley Lab: the company intends to commercialize the technique for industrial and biomedical.

In the coming months will work to develop new printing techniques that were complementary, that allow the use of a wider range of living materials and hybrids, to produce fabrics on an industrial scale.

Hans Garden

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